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Apocrine in breast tumor


tumor breast apocrine in


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Keratinous cysts with infundibular keratinization Isthmic epithelium Hair bulbs with papillary mesenchyme Matrical differentiation with basaloid, transitional and ghost cells Trichohyaline granules Anagen differentiation Sebaceous differentiation may include single cells or islands of mature sebocytes Metaplastic epithelial changes include clear cell change, columnar change, cytoplasmic vacuolization may be abortive luminal differentiation , hobnailing, mucinous, oxyphilic, squamous Metaplastic myoepithelial changes include clear cell change, collagenous spherulosis, hyaline cells, plasmacytoid cells, spindled cells Stroma: Mild nuclear pleomorphism within the ductal component Multinucleated, bizarre, hyperchromatic cells Features suggestive of malignancy include: Two different apocrine mixed tumors Source Microscopic histologic description Well circumscribed but unencapsulated, multilobulated mass in deep dermis or subcutaneous fat, with lobules separated by fibrous septae of varying width Biphasic with both epithelial and stromal components Epithelial: Most mixed tumors have both eccrine and apocrine components Sites Head and neck region involvement is common - nose is most common site here Extremities are less common - axilla is most common site here Case reports 39 year old man with tumor of external auditory canal Pathol Int ;


tumor breast apocrine in
tumor breast apocrine in
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tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in
tumor breast apocrine in

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